Anti-Human HLA-DQ Monomorphic – Purified,H135
Clone: 1a3
Product Type: Monoclonal Antibody
Isotype: Mouse IgG2a
Applications: FC
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Antibody Details
Formulation
This purified antibody is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Handling
This antibody is stable when stored at 2-8°C. Do not freeze.
Specificity
Anti-HLA-DQ (clone Ia3) recognizes a monomorphic epitope present on HLA-DQ molecules of the human class II major histocompatibility complex (MHC). Anti-HLA-DQ does not react with HLA-DR or HLA-DP molecules.
Antigen Distribution
The HLA-DQ antigen is present on approximately 10% of peripheral blood lymphocytes. This antibody reacts with virtually all B-cell lines and some tissue macrophages and dendritic cells.
Antigen Details
Ligand/Receptor
CD3/TCR, CD8
References & Citations
1. Wright, TM. et al. (2001) Arthritis Rheum. 44(7):1654-9. Article Link
2. Shookster, L. et al. (1987) Human Immunol. 20:59
Technical Protocols