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首页 ∷ 试剂 ∷ 近岸蛋白 ∷ Recombinant Human IL-4 (Mammalian)(Cat. No.:CX03)
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Recombinant Human IL-4 (Mammalian)(Cat. No.:CX03)

Recombinant Human IL-4 (Mammalian)(Cat. No.:CX03)

Recombinant Human Interleukin-4 is produced by our Mammalian expression system and the target gene encoding His25-Ser153 is expressed.

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商品描述

Recombinant Human Interleukin-4 is produced by our Mammalian expression system and the target gene encoding His25-Ser153 is expressed.

产品描述
Recombinant Human Interleukin-4 is produced by our Mammalian expression system and the target gene encoding His25-Ser153 is expressed.
蛋白编号
P05112
产品别称
Interleukin-4; IL-4; B-Cell Stimulatory Factor 1; BSF-1; Binetrakin; Lymphocyte Stimulatory Factor 1; Pitrakinra; IL4
分子量
14.97 KDa
表观分子量
18 KDa, reducing conditions
剂型描述
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
内毒素
Less than 0.001 ng/µg (0.01 EU/µg) as determined by LAL test.
纯度
Greater than 95% as determined by reducing SDS-PAGE.
生物活性
Loaded Human IL-4RA-His(Cat#CS33) on HIS1K Biosensor, can bind Human IL-4(Cat#CX03) with an affinity constant of 0.48 nM as determined in BLI assay. 
Loaded Human IL-4RA-Fc(Cat#CS38) on Protein A Biosensor, can bind Human IL-4(Cat#CX03) with an affinity constant of 0.99 nM as determined in BLI assay. 
Loaded Cynomolgus IL-4RA-His(Cat#C938) on HIS1K Biosensor, can bind Human IL-4(Cat#CX03) with an affinity constant of 0.33 nM as determined in BLI assay. 
Loaded Cynomolgus IL-4RA-Fc(Cat#C939) on Protein A Biosensor, can bind Human IL-4(Cat#CX03) with an affinity constant of 0.54 nM as determined in BLI assay. 
复溶

  • Always centrifuge tubes before opening.Do not mix by vortex or pipetting.

  • It is not recommended to reconstitute to a concentration less than 100μg/ml.

  • Dissolve the lyophilized protein in distilled water.

  • Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 

保存条件

  • Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.

  • Reconstituted protein solution can be stored at 4-7°C for 2-7 days.

  • Aliquots of reconstituted samples are stable at < -20°C for 3 months.

运输条件

  • The product is shipped at ambient temperature.

  • Upon receipt, store it immediately at the temperature listed below.

产品背景
Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response.
仅供科研或生产使用，不可直接应用于人体。