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L129320 Lopinavir ,≥99%

L129320 Lopinavir ,≥99%

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商品描述

基本信息

产品名称Lopinavir
英文名称Lopinavir
别名ABT-378;洛匹那韦
英文别名ABT-378;Aluviran; Koletra; ABT 378; ABT378;(2S)-N-[(2R,4S,5S)-5-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenyl-hexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide；(aS)-N-[(1S,3S,4S)-4-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-
应用Lopinavir has been used as a ZMPSTE24 and human immunodeficiency virus protease inhibitor.
规格或纯度≥99%
运输条件超低温冰袋运输
生化机理Lopinavir is an antiretroviral of the protease inhibitor class. Inhibition of HIV-1 protease prevents cleavage of the viral polyprotein precursor and results in the release of immature, noninfectious virions. A component of combination therapy to treat HIV/AIDS.

一般描述

Lopinavir is an antiviral HIV Protease Inhibitor. Lopinavir has insufficient bioavailability alone, so it is used in therapy in combination with Ritonavir, a HIV protease inhibitor, which inhibits cytochrome P450-3A4 (CYP3A4), a liver enzyme that normally metabolizes protease inhibitors. Lopinavir also has an ability to inhibit ZMPSTE24 (zinc metallopeptidase STE24).Lopinavir has been used as a ZMPSTE24 and human immunodeficiency virus protease inhibitor.


Lopinavir is an antiviral HIV Protease Inhibitor. Lopinavir has insufficient bioavailability alone, so it is used in therapy in combination with Ritonavir, a HIV protease inhibitor, which inhibits cytochrome P450-3A4 (CYP3A4), a liver enzyme that normally metabolizes protease inhibitors. Lopinavir also has an ability to inhibit ZMPSTE24 (zinc metallopeptidase STE24).
Lopinavir has been used as a ZMPSTE24 and human immunodeficiency virus protease inhibitor.

相关属性

CAS编号192725-17-0
熔点124-127°C
溶解性Soluble in DMF (~14 mg/ml), methanol, DMSO (126 mg/ml at 25 °C), water (< 1 mg/ml at 25 °C), and ethanol (126 mg/ml at 25 °C).
储存温度-20°C储存
分子量628.8
分子式C37H48N4O5
品牌阿拉丁
PubChem CID92727