无气味。能升华（260℃，2.00kPa）。微溶于冷水，较多溶于热水，几乎不溶于苯、乙醚、沸乙醇。饱和水溶液pH3.6。 有机合成。本品为医药中间体，主要用于制备异烟肼（雷米封）。也可以用它制异烟酰腙、酯类等衍生药物，农药工业也可以制抗倒胺等。
Application
Isonicotinic acid (IN) can be used as:
An organocatalyst in the one pot four component condensation reaction, to synthesize pyranopyrazoles based heterocyclic compounds.
An organic ligand for the preparation of copper(I) halide coordination polymer CuBr(IN)n, by hydrothermal method.
As a starting material for the synthesis of cation-dimers with potent antimalarial activity.It acts as an useful isomer of nicotinic acid.
相关属性
| CAS编号 | 55-22-1 |
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| 敏感性 | 对光敏感 |
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| 熔点 | 316°C |
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| 沸点 | 260°/15mm |
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| 溶解性 | Soluble in water (6 mg/ml), and 2 N NH4OH (5%). Insoluble in ether, benzene, and boiling alcohol. |
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| 储存温度 | 避光 |
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| RTECS | NS1103000 |
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| MDL号 | MFCD00006429 |
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| 密度 | 1.354 |
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| 分子量 | 123.11 |
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| 分子式 | C6H5NO2 |
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| EC号 | 200-228-2 |
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| 品牌 | 阿拉丁 |
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| Smiles | OC(=O)c1ccncc1 |
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| PubChem CID | 5922 |
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