English 简体中文
产品
文章
搜索
搜索
首页 ∷ 试剂 ∷ 近岸蛋白 ∷ Recombinant Mouse IL-4 (C-6His)(Cat. No.:CK74)
当前位置：
Recombinant Mouse IL-4 (C-6His)(Cat. No.:CK74)

Recombinant Mouse IL-4 (C-6His)(Cat. No.:CK74)

Recombinant Mouse Interleukin-4 is produced by our Mammalian expression system and the target gene encoding His21-Ser140 is expressed with a 6His tag at the C-terminus.

0.00
0.00
  
商品描述

Recombinant Mouse Interleukin-4 is produced by our Mammalian expression system and the target gene encoding His21-Ser140 is expressed with a 6His tag at the C-terminus.

产品描述
Recombinant Mouse Interleukin-4 is produced by our Mammalian expression system and the target gene encoding His21-Ser140 is expressed with a 6His tag at the C-terminus.
蛋白编号
P07750
产品别称
Interleukin-4; IL-4; IL4; B-cell IgG differentiation factor; B-cell growth factor 1; B-cell stimulatory factor 1; BSF-1; IGG1 induction factor; Lymphocyte stimulatory factor 1
分子量
14.6 KDa
表观分子量
15-19 KDa, reducing conditions
剂型描述
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
内毒素
Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
纯度
Greater than 95% as determined by reducing SDS-PAGE.
生物活性
Measured in a cell proliferation assay using M-NFS-60 mouse lymphoblast cells.  The ED50 for this effect is 0.035 ng/ml.
复溶

  • Always centrifuge tubes before opening.Do not mix by vortex or pipetting.

  • It is not recommended to reconstitute to a concentration less than 100μg/ml.

  • Dissolve the lyophilized protein in distilled water.

  • Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 

保存条件

  • Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.

  • Reconstituted protein solution can be stored at 4-7°C for 2-7 days.

  • Aliquots of reconstituted samples are stable at < -20°C for 3 months.

运输条件

  • The product is shipped at ambient temperature.

  • Upon receipt, store it immediately at the temperature listed below.

产品背景
Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response.
仅供科研或生产使用，不可直接应用于人体。