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首页 ∷ 试剂 ∷ 阿拉丁 ∷ A151027 阿托伐醌 ,≥98%
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A151027 阿托伐醌 ,≥98%

A151027 阿托伐醌 ,≥98%

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商品描述

基本信息

产品名称阿托伐醌
英文名称Atovaquone
别名阿托伐醌；反-2-[4-(4-氯苯基)环己基]-3-羟基-1,4-萘二酮
英文别名Mepron;trans-2-[4-(4-Chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthalenedione
应用Atovaquone may be used as a pharmaceutical secondary reference standard for the determination of the analyte in plasma samples by liquid-liquid extraction followed by reversed-phase high-performance liquid chromatography with ultraviolet detection.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
规格或纯度≥98%
运输条件超低温冰袋运输
生化机理Atovaquone is an anti-protozoal mitochondrial electron transport inhibitor; Antimalarial; Antipneumocystic, and has also been used to treat toxoplasmosis. It is an analog of protozoan mitochondrial protein ubiquinone, and acts by inhibiting the cytochrome bc(1) complex via interactions with the Rieske iron-sulfur protein and cytochrome b in the ubiquinol oxidation pocket.Antiparasitic agent. Protozoan ubiquinone analog. Inhibits coenzyme Q-complex III binding at the Qo cytochrome domain. Disrupts the protozoa electron transport chain. Active against Plasmodium spp., P. carinii, Babesia spp., and Toxoplasma go

一般描述

Atovaquone 用于治疗或预防肺孢子菌肺炎，弓形虫病, 疟疾和巴贝西虫。


Atovaquone is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia.Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Atovaquone belongs to the class of naphthoquinones with a broad-spectrum activity against parasitic infections including malaria, toxoplasmosis and Pneumocystis pneumonia. It is a potent antiprotozoal compound which aids in collapsing the mitochondrial membrane potential in a malaria parasite.


相关属性

CAS编号95233-18-4
敏感性对热敏感
熔点223 °C
溶解性不溶于水；极易溶于四氢呋喃；微溶于丙酮；不溶于甲醇
储存温度-20°C储存
RTECSQJ5616500
MDL号MFCD00889188
分子量366.84
分子式C22H19ClO3
品牌阿拉丁
备注如果有可能，您尽量在同一天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
PubChem CID74989