Bepotastine Beslilate also suppresses some allergic inflammatory processes such as allergic rhinitis, chronic urticaria or pruritus associated with skin conditions (eczema/dermatitis, prurigo or pruritus cutaneus).Bepotastine Beslilate (Bepreve) is useful for allergic conjunctivitis.Selective H 1 receptor antagonist. Stabilizes mast cell function. Inhibits eosinophilic infiltration. Inhibits IL-5 production, LTB4 and LTD4 activity. Shows antiallergic and antipruritic effects in vivo. Orally active.
Bepotastine is a non-sedating, selective antagonist of histamine 1 (H1) receptor with pIC50 of 5.7. Bepotastine Beslilate is a histamine H1 receptor anatagonist.
