Trehalose, Dihydrate, is an osmolyte, a chemical chaperone and inducer of autophagy, that has been reported to protect cells against numerous environmental stresses. This compound contains many properties that allow it to stabilize partially unfolded protein molecules and inhibit protein aggregation. These properties include a low chemical reactivity, high glass transition temperature, existence of numerous polymorphs, nonreducing nature, and high affinity for water molecules. Additionally, Trehalose has been noted to bind to expanded polyglutamines and stabilize partially unfolded polyglutamine-containing proteins.An osmolyte, chemical chaperone, and inducer of autophagy. Use as a cryoprotectant in a variety of cell freezing media.
Trehalose, Dihydrate, is an osmolyte, a chemical chaperone and inducer of autophagy, that has been reported to protect cells against numerous environmental stresses. This compound contains many properties that allow it to stabilize partially unfolded protein molecules and inhibit protein aggregation. These properties include a low chemical reactivity, high glass transition temperature, existence of numerous polymorphs, nonreducing nature, and high affinity for water molecules. Additionally, Trehalose has been noted to bind to expanded polyglutamines and stabilize partially unfolded polyglutamine-containing proteins.
An osmolyte, chemical chaperone, and inducer of autophagy.
相关属性
| CAS编号 | 6138-23-4 |
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| 敏感性 | 易吸潮 |
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| 比旋光度 | 181 ° (C=7, H2O) |
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| 熔点 | 97-99°C |
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| 溶解性 | Soluble in water (100 mg/ml), and hot alcohol. |
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| 储存温度 | 充氩 |
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| MDL号 | MFCD00071594 |
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| 密度 | 1.76 |
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| 分子量 | 378.33 |
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| 分子式 | C12H22O11·2H2O |
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| EC号 | 202-739-6 |
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| 品牌 | 阿拉丁 |
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| PubChem CID | 181978 |
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